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Maintaining Healthy Bones and Cardiovascular System with Vitamin K
The abundance of human clinical data underscores the critical role that vitamin K plays in maintaining healthy bone density and cardiovascular health. 1-5 Vitamin K facilitates the transport of calcium from the bloodstream into the bone, thereby supporting healthy bone density. Additionally, vitamin K is essential for the proper functioning of calcium-regulating proteins in the arteries.
One such protein is Matrix Gla-protein (MGP), a vitamin K-dependent protein that must be carboxylated to function correctly. Poor vitamin K status leads to the accumulation of inactive, uncarboxylated MGP (ucMGP) at sites of arterial calcification. 6,7 Since MGP is a potent local inhibitor of arterial calcification, its importance extends to the overall health of the cardiovascular system. Without adequate vitamin K, calcium in the blood can bind to the arterial wall, resulting in calcification. 8,9 Even a subclinical vitamin K deficiency can pose risks to the vascular system as people age.
Poor vitamin K status also results in increased circulating levels of undercarboxylated osteocalcin, which is associated with increased bone loss in postmenopausal women.
Vitamin K2 has been shown to support heart health, as higher intakes of this form of vitamin K correspond with better arterial health. The reason for this is that K2 facilitates the process of moving calcium out of the bloodstream and into the bones, where it belongs.
When it comes to vitamin K, K2 is up to 10 times more bioavailable than K1, which means it can remain biologically active in the body for longer. Additionally, the menaquinone-7 form of K2 metabolizes more slowly, providing a more consistent supply to the body.
Supplementation can be a valuable alternative to obtaining vitamin K2 from dietary sources, as not all dietary K2 choices are the healthiest, and you often need large amounts of food to get optimal amounts.
At our company, we use only the finest raw ingredients with the purity and potency you deserve. The majority of our products are non-GMO, gluten-free, and manufactured in the USA, with a Certificate of Analysis available for every one.
We believe that the answers to a healthier life are within reach, and that scientific research is the key to getting us there. That's why so many of our formulas feature specific ingredients and amounts based on scientific studies, all with the goal of helping you live your healthiest life.
product information:
Attribute | Value | ||||
---|---|---|---|---|---|
is_discontinued_by_manufacturer | No | ||||
product_dimensions | 1.75 x 1.75 x 3.25 inches; 0.02 ounces | ||||
item_model_number | 01936 | ||||
date_first_available | November 8, 2008 | ||||
manufacturer | Life Extension | ||||
country_of_origin | USA | ||||
best_sellers_rank | #13,192 in Health & Household (See Top 100 in Health & Household) #1,579 in Sales & Deals | ||||
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